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The No. 1 Cause of Disability: Arthritis

Think of how many times you've heard people say, as they groaned getting out of a chair, "I guess I'm getting old."

"Anyone who has significant [joint] pain should get an evaluation," says David S. Pisetsky, M.D., professor of rheumatology at Duke University.

Arthritis is the number one cause of disability in the United States. Nearly 70 million Americans reported having diagnosed arthritis or chronic joint symptoms in a Centers for Disease Control and Prevention (CDC) survey conducted in 2001.

Unfortunately, many people with arthritis believe that nothing can be done. The CDC found that half of the people in the survey had not seen a doctor for their arthritis symptoms. Yet, early treatment for rheumatoid arthritis (RA) often is critical. Most of the damage to joints can occur within the first two years of onset of RA, experts say.


What is arthritis?
Arthritis is a disease that affects the joints. Some forms of arthritis also affect muscles and connective tissue, including the skin and internal organs. There are 100 types of arthritis. Older adults most often develop osteoarthritis (OA), the most common type of arthritis. OA is a degenerative joint disease that can come on gradually or suddenly, says Dr. Pisetsky.

Rheumatoid arthritis is the second most common type of arthritis, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). It is an inflammatory disease that causes pain, swelling, stiffness and loss of function in the joints. This loss of function is in a symmetrical pattern: If one knee or hand is involved, usually the other one is also. RA can also affect other parts of the body besides the joints. In addition, people with the disease may have fatigue, occasional fever and a general sense of not feeling well.


Causes of arthritis
The causes of arthritis vary. Arthritis can be degenerative (such as OA) or inflammatory (such as RA). In OA, the process affects the cartilage at the ends of bones. Worn cartilage no longer allows bones to slide smoothly past each other. RA is a disease that affects the body's immune system. RA causes inflammation in the joint lining.

Researchers have identified some risk factors for arthritis. RA and arthritis caused by lupus are more common in women, but arthritis caused by ankylosing spondylitis is more common in men. Gout is more common in older men. Some forms of arthritis tend to run in families. Some arthritis can develop from trauma to a joint or through overuse. Studies have also shown that OA can be caused by a genetic defect in components of cartilage called collagen.

Experts say that what's critical in arthritis is an early diagnosis. That way, treatment can begin before too much damage occurs to the joints. The three main symptoms of arthritis are joint pain that lasts for more than two weeks, joint stiffness or an inability to move the joint normally, and occasionally swelling. "Don't ignore joint pain," Dr. Pisetsky warns.




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