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Achalasia is a disorder of the tube that carries food from the mouth to the stomach (esophagus), which affects the ability of the esophagus to move food toward the stomach

Esophageal achalasia

The main problem in achalasia is a failure of the a muscular ring where the esophagus and stomach come together (lower esophageal sphincter) to relax during swallowing.

Another part of the disorder is a lack of nerve stimulation to the muscles of the esophagus. Causes include:

• Cancers
• Damage to the nerves of the esophagus
• Infection with a parasite
• Inherited factors

As a result, the wave-like contractions of smooth muscles that normally force food through the esophagus and other parts of the digestive tract do not work as well. (These contractions are called peristalsis.)

Achalasia is a rare disorder. It may occur at any age, but is most common in middle-aged or older adults.

• Backflow (regurgitation) of food
• Chest pain, which may increase after eating or may radiate to the back, neck, and arms
• Cough
• Difficulty swallowing liquids and solids
• Heartburn
• Unintentional weight loss

Physical examination may show signs of anemia.

Tests include:

• Esophageal manometry
• Upper GI x-ray

The outcomes of surgery and nonsurgical treatments are similar. Sometimes more than one treatment is necessary.

• Breathing food contents into the lungs, which can cause pneumonia
• Regurgitation of acid or food from the stomach into the esophagus (reflux)
• Tearing (perforation) of the esophagus

Call your health care provider if you have difficulty swallowing or painful swallowing, or if your symptoms continue despite treatment for achalasia.

Many of the causes of achalasia are not preventable. However, treatment of the disorder may help to prevent complications.