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tolerance (tol´әr-әns)   the ability to bear something potentially difficult.
  the ability to endure unusually large doses of a poison or toxin.
  drug tolerance. adj., tol´erant., adj.
 

acquired drug tolerance  drug tolerance.

drug tolerance  a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response. See also drug dependence and habituation.

immunologic tolerance  specific nonreactivity of lymphoid tissues to a particular antigen that under other conditions should produce immunity.





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