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tolerance (tol´әr-әns) the ability to bear something potentially difficult. the ability to endure unusually large doses of a poison or toxin. drug tolerance. adj., tol´erant., adj. acquired drug tolerance
drug tolerance. drug tolerance
a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response.
See also drug dependence and habituation. immunologic tolerance
specific nonreactivity of lymphoid tissues to a particular antigen that under other conditions should produce immunity.
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