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lupus erythematosus(LE) (loo´pәs er″ә-them″ә-to´sәs) a group of connective tissue disorders primarily affecting women aged 20 to 40, comprising a spectrum of clinical forms in which cutaneous disease may occur with or without systemic involvement. The two principal types are cutaneous lupus erythematosus and systemic lupus erythematosus.
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