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Graves disease (grāvz)   a syndrome in which thyrotoxicosis is associated with diffuse goiter, infiltrative exophthalmos, and sometimes infiltrative dermopathy. It is now known to be an autoimmune disease; most patients with this condition have autoantibodies against thyroglobulin, thyroid microsomes, and often some components of the thyroid cell membrane. Other symptoms and signs include hand tremors, nausea, diarrhea, increased metabolism, heavy sweating, nervous irritability, skin changes, hyperglycemia, anemia, and tachycardia.




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