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hemophilia (he″mo-filŽe-ә) a hereditary disorder characterized by a strong tendency to bleed. The most common types are carried as sex-linked genes with females carrying the trait and disease manifestations almost always in males. All daughters of affected men will be carriers for the gene of hemophilia. The two most common types are hemophilia A and hemophilia B. Other coagulation factor deficiencies are less common, with patients suffering either milder bleeding or thrombotic episodes. Bleeding in hemophilic patients is variable, depending on the level of deficiency of the coagulation factor. Approximately 60 per cent of persons with hemophilia A or B are severely affected and may have spontaneous bleeding without any recognized trauma. hemophilia A
the most common type of hemophilia (q.v.), an X-linked condition caused by deficiency of factor VIII. Called also classical hemophilia. hemophilia B
a common type of hemophilia, an X-linked condition caused by deficiency of factor IX. Called also Christmas disease. hemophilia C
factor XI deficiency. classical hemophilia
hemophilia A.
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