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hydronephrosis (hi″dro-nә-fro´sis) distention of the renal pelvis and calices with urine as a result of obstruction or atrophy of the urinary tract. Symptoms include recurrent pain in the kidney region, pus and blood in the urine, and fever if infection develops. If both kidneys are involved, there will be uremia as the functional units of the kidneys are destroyed. The collecting tubules dilate and the muscular walls of the pelvis and calices stretch, are replaced by fibrous tissue, and eventually form a large, fluid-filled, functionless sac. adj., hydronephrot´ic., adj.

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