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kallikrein (kal″ĭ-kreŽin)   any of several serine endopeptidases that cleave kininogens to form kinins.
 

plasma kallikrein  a hydrolytic enzyme of the plasma that cleaves HMW (high-molecular-weight) kininogen to produce bradykinin. It also activates several blood coagulation factors and plasminogen. It is formed from prekallikrein by activated coagulation factor XII.

tissue kallikrein  a hydrolytic enzyme that cleaves LMW kininogen to produce kallidin. It and closely related forms are found in tissues and various glandular secretions such as lymph, pancreatic juice, urine, and saliva.





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