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luteinizing hormone(LH) an anterior pituitary hormone that is a gonadotropin and acts with follicle-stimulating hormone to cause ovulation of mature graafian follicles and secretion of estrogen by theca cells and granulosa cells of the ovary; it is also concerned with corpus luteum formation. In the male, it stimulates development of the Leydig cells of the testes and their secretion of testosterone. Called also interstitial cell–stimulating hormone.
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