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mechlorethamine (mek″lor-eth´ә-mēn)   an alkylating agent that produces interstrand and intrastrand cross-linkages in DNA to cause miscoding, breakage, and failure of replication. Used primarily for the treatment of disseminated Hodgkin disease, especially in the MOPP treatment regimen, and for other lymphomas, including mycosis fungoides; administered intravenously as the hydrochloride salt. Called also nitrogen mustard.




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