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painful bruising syndrome a purpuric reaction seen chiefly in young to middle-aged women in which spontaneous, chronic recurring painful ecchymoses occur on the body without antecedent trauma or after insufficient trauma; these may be precipitated by emotional stress. Based on studies that show that certain patients exhibit autoerythrocyte sensitization in which intradermal injection of their own erythrocytes produces a painful ecchymosis, the etiology of the condition has been ascribed by some to an autosensitivity to a component of the erythrocyte membrane; others consider it to be of psychosomatic or factitious origin. Called also autoerythrocyte sensitization syndrome.

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