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ventricular septal defect a congenital heart defect in which the opening in the ventricular septum (normal in the fetus) persists after birth, in either the muscular or fibrous portion, most often due to failure of the bulbar septum to completely close the interventricular foramen. This permits flow of blood directly from one ventricle to the other, resulting in bypassing of the pulmonary circulation and varying degrees of cyanosis. Defective valves affecting the flow of blood to and from the heart may also be present.

Abnormal communication between the ventricles in ventricular septal defect.

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