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spina bifida (spi´nә bif´ĭ-dә) a developmental anomaly characterized by defective closure of the vertebral column and its encasement of the spinal cord; the spinal cord and meninges may or may not protrude through the defect (see spina bifida cystica and spina bifida occulta). It is further classified according to the extent of neural involvement (see meningocele and meningomyelocele). See also neural tube defect.
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