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alpha-fetoprotein(AFP)
(al″fә-fe″to-pro´tēn)
α-fetoprotein
(fe″to-pro´tēn)
a plasma protein produced by the fetal liver, yolk sac, and gastrointestinal tract and also by hepatocellular carcinoma, germ cell neoplasms, and other cancers in adults; elevated levels may also be seen in benign liver disease such as cirrhosis and viral hepatitis. The serum AFP level is used to monitor the effectiveness of cancer treatment. During pregnancy some AFP crosses from the
amniotic fluid to the mother's blood. If the fetus has a neural tube defect, large amounts of AFP will be found in the amniotic fluid and maternal blood.

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