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activation (ak″tĭ-va´shәn) the act or process of rendering active. the transformation of a proenzyme into an active enzyme by the action of a kinase or another enzyme. the process by which the central nervous system is stimulated into activity through the mediation of the reticular activating system. the deliberate induction of a pattern of electrical activity in the brain. allosteric activation
increase in enzyme activity by binding of an effector at an allosteric site that affects binding or turnover at the catalytic
site. contact activation
initiation of the intrinsic pathway of coagulation through interaction of coagulation factor XII with various electronegative
surfaces.
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