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aldosteronism (al-dos´tә-ro-niz″әm) an abnormality of electrolyte metabolism caused by excessive secretion of aldosterone, it may be primary or may be seen secondary to a disease outside the adrenal glands. There may be hypertension, hypokalemia, alkalosis, muscular weakness, polyuria, and polydipsia. Called also hyperaldosteronism. primary aldosteronism
that arising from oversecretion of aldosterone, characterized typically by hypokalemia, alkalosis, muscular weakness, polyuria,
polydipsia, hypertension, cardiac irregularity, and tetany. The most common etiologic factors are adrenal adenoma, idiopathic
hyperplasia of the adrenal cortex, and occasionally carcinoma of the adrenal gland. Most adenomas affect only one of the two
glands and therefore can be removed surgically without depriving the patient of a sufficient supply of adrenal cortical hormones.
If removal of both glands is necessary, this creates a serious and potentially fatal insufficiency of the hormones. Called
also Conn syndrome. pseudoprimary aldosteronism
that caused by bilateral adrenal hyperplasia and having the same signs and symptoms as primary aldosteronism. secondary aldosteronism
that due to extra-adrenal stimulation of aldosterone secretion; it is commonly associated with edematous states, as in nephrotic
syndrome, cirrhosis, heart failure, and accelerated hypertension.
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