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amplification (am″plĭ-fĭ-ka´shәn)   the act or result of increasing in number, size, power, or other variable, such as the increase of an auditory or visual stimulus as a means of improving its perception.
 

DNA amplification  an in vitro nucleic acid amplification technique in which a DNA segment is amplified.
  a term sometimes used to denote in vivo gene amplification, particularly that associated with malignancy.

gene amplification  selective replication of a specific gene or genes disproportionate to their representation in the parent molecule, such as that occurring in specific cells in response to signals of cell development or to stress from the environment. In humans this process is seen most often in malignant cells.
  a term sometimes used to mean an in vitro nucleic acid amplification technique, even though the sequence amplified may not correspond precisely to a gene.

nucleic acid amplification  increase in the number of copies of a specific nucleic acid sequence, either DNA or RNA; usually used to denote any of various in vitro techniques employed to aid detection of a nucleic acid sequence of interest. The original, and still most commonly used, technique is the polymerase chain reaction.





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