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antagonist (an-tag´ә-nist) antagonistic muscle. a substance that tends to nullify the action of another, as a drug that binds to a cellular receptor for a hormone, neurotransmitter, or another drug blocking the action of that substance without producing any physiologic effect itself. See also blocking agent. a tooth in one jaw that articulates with one in the other jaw. α-adrenergic antagonist
alpha-adrenergic blocking agent. β-adrenergic antagonist
beta-adrenergic blocking agent. H1 receptor antagonist
any of a large number of agents that block the action of histamine by competitive binding to the H1 receptor. Such agents also have sedative, anticholinergic, and antiemetic effects, the exact effect varying from drug to
drug, and are used for the relief of allergic symptoms and as antiemetics, antivertigo agents, sedatives, and antidyskinetics
in parkinsonism. This group is traditionally called the antihistamines. H2 receptor antagonist
an agent that blocks the action of histamine by competitive binding to the H2 receptor; used to inhibit stomach secretions in the treatment of peptic ulcers.
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