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scleroderma
(sklēr″o-durīmә)
chronic hardening and shrinking of the connective tissues of any organ of the body, such as the skin, heart, esophagus, kidney, or lung; the cause is unknown. The skin may be thickened, hard, and rigid, and pigmented patches may occur. The milder forms are
most often seen in women between the ages of 30 and 50; the more severe forms usually affect men, African Americans, and older
persons.
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