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denaturation
(de-na″chәr-a´shәn)
a change in the usual nature of a substance, as by the addition of methanol or acetone to alcohol to render it unfit for drinking,
or the change in the physical properties of a substance, such as a protein or nucleic acid, caused by heat or certain chemicals
that alter tertiary structure.
protein denaturation
any nonproteolytic change in the chemistry, composition, or structure of a native protein that causes it to lose some or all
of its unique or specific characteristics.
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