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desensitization (de-sen″sĭ-tĭ-za´shәn) the prevention or reduction of immediate hypersensitivity by administration of graded doses of allergen; see also immunotherapy. Called also hyposensitization. in behavior therapy, the treatment of phobias and related disorders by intentionally exposing the patient, in imagination or in real life, to a hierarchy of emotionally distressing stimuli.
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