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plasma cell dyscrasias  a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocytic or lymphoplasmacytic morphology. The group includes multiple myeloma, Waldenström macroglobulinemia, the heavy chain diseases, and benign monoclonal gammopathy. Called also paraproteinemias and monoclonal gammopathies.




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