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elephantiasis (el″ә-fәn-ti´ә-sis) a type of secondary lymphedema that reaches massive proportions, with hypertrophy of the skin and subcutaneous tissues (pachyderma), usually of a lower limb or the scrotum, caused by chronic obstruction of lymphatic vessels. It is a filarial disease generally seen in the tropics due to infection of the lymphatics with any of the nematodes Wuchereria bancrofti, Brugia malayi, or Brugia timori. It begins with lymphangitis and enlargement of the part, along with chills and fever, followed by formation of ulcers and tubercles with thickening, discoloration, and fissuring of the skin.
hypertrophy and thickening of the tissues from any cause.

elephantiasis nostras swelling of a lower limb from chronic streptococcal erysipelas or chronic recurrent cellulitis.

elephantiasis scroti that affecting mainly the scrotum.

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