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estradiol (es″trә-diŽol) (es-traŽde-ol)   the most potent naturally occurring ovarian and placental estrogen in mammals; it prepares the uterus for implantation of the fertilized oocyte and promotes the maturation of and maintenance of the female accessory reproductive organs and secondary sex characters.
  a preparation of this hormone used in estrogen replacement therapy for conditions such as female hypogonadism, ovariectomy, or primary ovarian failure, and in treatment of abnormal uterine bleeding, vasomotor menopausal symptoms, postmenopausal osteoporosis, atrophic vaginitis, and certain advanced breast or prostatic carcinomas. Used most often in the form of estradiol cypionate, estradiol valerate, or ethinyl estradiol.




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