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estrone (esītrōn)   an estrogen isolated from pregnancy urine, the human placenta, and palm kernel oil, and also prepared synthetically; used in estrogen replacement therapy for hypogonadism, ovariectomy, primary ovarian failure, atrophic vaginitis, vasomotor menopausal symptoms such as hot flashes, and vulvar atrophy, and in the treatment of dysfunctional uterine bleeding and advanced prostate cancer. Administered intramuscularly or intravaginally. See also conjugated estrogens and esterified estrogens.




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