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factor V
proaccelerin: a coagulation factor that is heat- and storage-labile, present in plasma but not in serum, and functions in both the intrinsic and extrinsic pathways of coagulation. It catalyzes the cleavage of prothrombin to the active thrombin. Deficiency of this factor, an autosomal recessive trait, leads to a rare hemorrhagic tendency called parahemophilia, with varying degrees of severity. Called also accelerator globulin.
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