| |
creatine
(kreŽә-tin)
a nonprotein substance synthesized in the body from three amino acids: arginine, glycine (aminoacetic acid), and methionine.
Creatine readily combines with phosphate to form phosphocreatine, or creatine phosphate, which is present in muscle, where
it serves as the storage form of high-energy phosphate necessary for muscle contraction.
creatine kinase
an enzyme catalyzing the transfer of a phosphate group from phosphocreatine to ATP. It has three isoenzymes: CK1, found primarily in the brain; CK2, found in the myocardium; and CK3, found in both skeletal muscle and the myocardium. The presence of CK2 in the blood is strongly indicative of a recent myocardial infarction; it is present until about 72 hours after the attack.
Copyright 2007. An Elsevier publication. All rights reserved.
Click here for important legal information about Dorland's Medical Dictionary.
|
