
	3D Medical Animations Close This information is provided by an independent source. Merck & Co. does not endorse and is not responsible for the accuracy of the content, or for the practices or standards of non-Merck sources. This information provided is not intended to be a substitute for professional medical advice. A licensed healthcare professional should be consulted for diagnosis and treatment of any and all medical conditions. The manufacturer of a product generally has the most complete information about that product. How to use How to use The world's largest library of 3D medical animations developed and copyrighted by Blausen Medical Communications. The Human Atlas figures rotating model, labeled slides, and printable text in addition to animated videos. Shows a video of the selected health topic. Controls play, pause, and restart of the video. Shows a summary of the selected health topic. Controls to scroll the text. Shows a 3 D model of the video. Controls to rotate the model. Shows slides from the video. Controls to change slides.

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cytotoxicity (si″to-tok-sis´ĭ-te) the degree to which an agent has specific destructive action on certain cells.
the possession of such destructive action, particularly in reference to lysis of cells by immune phenomena and to antineoplastic agents that selectively kill dividing cells. adj., cytotox´ic., adj.

antibody-dependent cell-mediated cytotoxicity(ADCC) , antibody-dependent cellular cytotoxicity lysis of target cells coated with antibody by effector cells with cytolytic activity and specific immunoglobulin receptors called Fc receptors, including K cells, macrophages, and granulocytes. Lysis of the target cell is extracellular, requires direct cell-to-cell contact, and does not involve complement.

cell-mediated cytotoxicity destruction of a target cell by specific lymphocytes, such as cytotoxic T lymphocytes or NK cells; it may be antibody-dependent (see antibody-dependent cell-mediated c.) or independent, as in certain cell-mediated hypersensitivity reactions.

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