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Parkinson disease (pahrŽkin-sәn)   a slowly progressive disease usually occurring in later life, characterized pathologically by degeneration within the nuclear masses of the extrapyramidal system, and clinically by a masklike face (Parkinson facies), a characteristic tremor of resting muscles, a slowing of voluntary movements, a festinating gait, peculiar posture, and muscular weakness. Called also paralysis agitans and shaking palsy. When the symptom complex occurs secondarily to another disorder, the condition is called parkinsonism.




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