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estrogen (esītrә-jen) a generic term for any of the estrus-producing compounds (female sex hormones), including estradiol, estriol, and estrone. In humans these are formed in the ovary, adrenal cortex, testis, and fetoplacental unit, and they are responsible for the development of female secondary sex characters. During the menstrual cycle they act on the female genitalia to produce an environment suitable for fertilization, implantation, and nutrition of the early embryo. Uses for estrogens include oral contraceptives, hormone replacement therapy, treatment of advanced prostate or postmenopausal breast carcinoma, and prophylaxis of osteoporosis. Called also estrogenic hormone. conjugated estrogens
a mixture of the sodium salts of the sulfate esters of estrone and equilin; therapeutic uses are similar to those of other estrogens; administered orally, intravenously, intramuscularly, or intravaginally. esterified estrogens
a mixture of esters of estrogenic substances, principally estrone, having therapeutic uses similar to those of other estrogens.
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