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Helicobacter pylori

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Where Ulcers Form
An ulcer (a sore or crater) can form in two main areas of the digestive tract–in the duodenum, the space where the stomach meets the small intestine, and in the stomach itself. These areas contain strong acids and enzymes that help digest the food you eat. To keep these substances from also digesting your body's own tissue, the stomach and duodenum are coated with a protective mucus layer.

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How H. pylori Cause Ulcers
H. pylori bacteria are common and can be passed from one person to another. When H. pylori enter the body, they like to hide in the protective mucus layer coating your stomach and duodenum. The bacteria weaken this mucus layer and irritate the tissue underneath. Acid may flow through the weakened mucus layer and burn the underlying inflamed tissue. These factors may lead to formation of an ulcer in the lining of the stomach or duodenum.

H. pylori invade and disturb the protective mucus layer.

Acid may pass through the weakened mucus layer, causing an ulcer.

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Last Revised 07/2009 20351091(1)-12/03-EBS-CON

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